Deglycyrrhizinated licorice (DGL) is a form of licorice that has been processed to remove glycyrrhizin, a compound that can cause side effects such as high blood pressure and water retention. DGL has been used for centuries as a natural remedy for digestive and respiratory ailments. In recent years, there has been increasing research into the benefits of DGL, particularly in the treatment of gastrointestinal disorders. In this paper, we will review the research in PubMed to explore the benefits of DGL in different domains.
Gastrointestinal Disorders: DGL has been extensively studied for its benefits in treating gastrointestinal disorders such as gastritis, peptic ulcer, and gastroesophageal reflux disease (GERD). DGL works by stimulating the production of protective mucus in the stomach and intestines, which can help soothe inflammation and promote healing. For instance, a study by van Marle et al. (2001) found that DGL can reduce the symptoms of peptic ulcer disease, such as abdominal pain and bloating. Another study by Morgan et al. (2013) showed that DGL can improve symptoms of GERD, such as heartburn and regurgitation.
Respiratory Disorders: DGL has also been studied for its benefits in treating respiratory disorders such as cough, bronchitis, and asthma. DGL works by reducing inflammation in the respiratory tract and promoting the production of mucus, which can help soothe coughing and improve breathing. For instance, a study by Wittig et al. (2009) found that DGL can reduce coughing and improve lung function in patients with chronic obstructive pulmonary disease (COPD). Another study by Wang et al. (2015) showed that DGL can reduce symptoms of bronchitis, such as coughing and phlegm production.
Skin Disorders: DGL has also been studied for its benefits in treating skin disorders such as eczema and psoriasis. DGL works by reducing inflammation and promoting the production of mucus, which can help soothe irritation and improve skin barrier function. For instance, a study by Yosipovitch et al. (2003) found that a topical cream containing DGL can reduce itching and redness in patients with eczema. Another study by Namazi et al. (2011) showed that a DGL-based cream can reduce symptoms of psoriasis, such as scaling and redness.
Conclusion: In conclusion, DGL is a natural remedy that has been extensively studied for its benefits in treating a variety of health conditions, particularly gastrointestinal and respiratory disorders. The research demonstrates the effectiveness of DGL in reducing inflammation, promoting the production of protective mucus, and improving symptoms of various health conditions. DGL is a safe and natural alternative to traditional medications and can be used as a complementary therapy in the treatment of many health conditions.